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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARCKS All Species: 21.52
Human Site: S147 Identified Species: 59.17
UniProt: P29966 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29966 NP_002347.5 332 31555 S147 D G A T P S P S N E T P K K K
Chimpanzee Pan troglodytes XP_001159872 332 31614 S147 D G A T P S P S N E T P K K K
Rhesus Macaque Macaca mulatta XP_001082393 330 31424 S146 D G A T P S P S N E T P K K K
Dog Lupus familis XP_855257 346 32726 S156 D G A A P S P S G E T P K K K
Cat Felis silvestris
Mouse Mus musculus P26645 309 29643 S140 D G A A P S P S S E T P K K K
Rat Rattus norvegicus P30009 309 29776 S140 D G A A P S P S S E T P K K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P16527 281 27710 G152 E G A E S E G G A A A A A E G
Frog Xenopus laevis NP_001080075 287 29046 A160 E G A E N E G A V A S T E E A
Zebra Danio Brachydanio rerio NP_001019575 236 24455 K115 E T P K K K K K R F S F K K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.4 66.7 N.A. 68.9 68.9 N.A. N.A. 60.8 53.6 44.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 98.8 72.5 N.A. 75.3 77.4 N.A. N.A. 68 60.2 50.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. N.A. 13.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. 26.6 46.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 89 34 0 0 0 12 12 23 12 12 12 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 34 0 0 23 0 23 0 0 0 67 0 0 12 23 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 12 0 12 0 0 0 % F
% Gly: 0 89 0 0 0 0 23 12 12 0 0 0 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 12 12 12 12 12 0 0 0 0 78 78 67 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 12 0 0 0 34 0 0 0 0 0 0 % N
% Pro: 0 0 12 0 67 0 67 0 0 0 0 67 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 12 67 0 67 23 0 23 0 0 0 12 % S
% Thr: 0 12 0 34 0 0 0 0 0 0 67 12 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _